Seal of the State of Nevada

WHEREAS, Rett syndrome is a rare postnatal genetic neurological disorder that occurs in females almost exclusively. It is estimated that 1 in every 10,000 live female births is affected by Rett syndrome across all racial and ethnic groups worldwide, but its symptoms usually do not appear until age 6 to 18 months; and

WHEREAS, a regression period follows where acquired motor skills are lost, leading to lifelong impairments, including loss of speech, seizures, scoliosis, and irregular breathing patterns. More than half of those affected with Rett syndrome lose their ability to walk and the hallmark sign of Rett syndrome is near constant repetitive hand movements while awake; and

WHEREAS, those diagnosed with Rett syndrome require maximum assistance with daily living activities for their entire lives; and

WHEREAS, the disorder is not degenerative and biomedical research in mice suggests that neurological symptoms may be reversed even after decades of severe symptoms; and

WHEREAS, with the discovery of the gene that causes Rett syndrome, research in the lab with mice proves the theory of reversibility of the disease, the discovery of breakthrough testing in vitro models and the launch of five disease-modifying human clinical trials, members of the Rett syndrome community have reached an unprecedented and historic moment in time where they must continue to advocate for research that creates truly life-changing solutions for all with Rett syndrome; and

WHEREAS, in Nevada we must continue our efforts in bringing awareness to the medical community, pharmaceutical industry, researchers, therapists, teachers, caregivers, and the general public; and

WHEREAS, as Nevadans we must continue to advocate for funding for researchers who are dedicated to finding a cure for Rett syndrome and support the shared mission in progressing towards a world without Rett syndrome;

NOW, THEREFORE, I, STEVE SISOLAK, GOVERNOR OF THE STATE OF NEVADA, do hereby proclaim the month of October 2021, as

RETT SYNDROME AWARENESS MONTH IN NEVADA

Footer State Seal

IN WITNESS WHEREOF, I have hereunto set my hand and caused the Great Seal of the State of Nevada to be affixed at the State Capitol in Carson City, this 24th day of September, 2021

Governor's signature