Seal of the State of Nevada

WHEREAS, Phelan-McDermid Syndrome, also known as 22q13 deletion syndrome, is a rare genetic condition caused by a deletion or other structural change of the terminal end of chromosome 22 in the 22q13 region or a disease-causing mutation of the SHANK3 gene; and

WHEREAS, according to the Phelan-McDermid Syndrome Foundation, a fluorescence in situ hybridization (FISH) test, or whole exome sequencing (WES) is recommended to confirm a diagnosis of this genetic condition; and

WHEREAS, individuals, parents and advocacy groups can increase awareness of Phelan-McDermid Syndrome and its symptoms through educational opportunities and informational exchange; and

WHEREAS, although the range and severity of symptoms may vary, Phelan-McDermid Syndrome is generally characterized by intellectual disability of varying degrees, delayed or absent speech, symptoms of autism spectrum disorder, low muscle tone, motor delays, and epilepsy; and

WHEREAS, it is important to raise awareness of Phelan-McDermid Syndrome and promote education that will help inform citizens about this disease;

NOW, THEREFORE, I, STEVE SISOLAK, GOVERNOR OF THE STATE OF NEVADA, do hereby proclaim October 22, 2019, as

PHELAN-MCDERMID SYNDROME AWARENESS DAY

Footer State Seal

IN WITNESS WHEREOF, I have hereunto set my hand and caused the Great Seal of the State of Nevada to be affixed at the State Capitol in Carson City, this 10th day of October, 2019

Governor's signature